Everything you need to know
about stem cell research
Fr. Seamus Hogan
Special to The Interim
There
are many issues of importance in the realms of human reproduction and
genetics: From birth control and abortion to in-vitro fertilization
and cloning. Today, though, I would like to talk about a topic that
is no less relevant to us; that is, stem cell research and what it means
to us as Christians.
Let's begin at the beginning. What is a stem cell? A stem cell is a
relatively unspecialized cell that, when it divides, can do two things:
make another cell like itself, or (and here's why they're so interesting
to researchers) make any number of cells with more specialized functions.
For example, just one kind of stem cell in our blood can make new red
blood cells, or white blood cells, or other kinds - depending on what
the body needs. These cells are like the stem of a plant that spreads
out in different directions as it grows; hence, the name "stem cells."
Many people, including Catholics, believe that the church is opposed
to all stem cell research. This is simply not the case. Most stem cell
research uses cells obtained from adult tissue, umbilical cord blood,
and other sources that pose no moral problem. Useful stem cells have
been found in bone marrow, blood, muscle, fat, nerves and even the pulp
of baby teeth. Some of these cells are already being used to treat people
with a wide variety of diseases. Such research is morally permissible.
In fact, such research has shown promising results. Adult stem cells
have been used in bone marrow transplants and in treatments of blood
disorders and leukemia. Companies using adult stem cells are currently
conducting clinical tests on treatments for heart attacks, liver disease,
bone and cartilage diseases, and brain disorders, including Parkinson's
disease. Dr. Paul Sharkins of John Hopkins University recently published
a study in which bone marrow stem cells from animal donors were converted
into healthy liver cells. He stated that, "It is mind-blowing stuff.
I never would have thought this possible."
The difficulty for the church and for people of good will, regardless
of religion, is when embryonic stem cells are used in research. These
stem cells are obtained by producing an embryo in-vitro (i.e., in the
laboratory) by fertilizing an ovum (egg), allowing it to develop for
a few days in a petri dish and then extracting the cells, thereby killing
the embryo. This research produces difficulty, because the harvesting
of these stem cells kills the living human embryo. The church opposes
the direct destruction of innocent human life for any purpose, including
research.
As a church, we have consistently asserted that a human being must
be respected as a person from the first moment of conception, the very
first instance of existence. Each person is made in the image and likeness
of God, and thereby has an inherent dignity beyond the rest of creation.
The church's Declaration on Procured Abortion states, "From the time
that the ovum is fertilized, a new life is begun which is neither that
of the father nor of the mother; it is, rather, the life of a new human
being with its own growth. It would never be made human if it were not
already human." To this perpetual evidence, modern genetic science brings
valuable confirmation. Science has demonstrated that, "At the moment
the sperm cell of the human male meets the ovum of the female and the
union results in a fertilized ovum (zygote), a new life has begun."
Thus, the issue is not whether human life is present from the moment
of conception, but how society ought to treat it. Clearly, human beings
are not simply disposable biological material.
So is the church telling us to choose the lives of embryos over the
lives of suffering patients? No. It is calling us to respect both, without
discrimination. We must help those who are suffering, but we may not
use a good end to justify an evil means. Moreover, treatments that do
not require destroying any human life are at least as promising - they
are already healing some conditions and are far closer to healing other
conditions than any approach using embryonic stem cells. The choice
is not between science and ethics, but between science that is ethically
responsible and science that is not.
In spite of this, many believe that embryonic stem cells are the most
effective for treating disease. But this, simply, is not the case. Embryonic
stem cells have not helped a single human patient or demonstrated any
therapeutic benefit, and animal trials suggest that they are too genetically
unstable and too likely to form lethal tumours to be used for treatment
anytime soon. By contrast, adult stem cells and other ethically acceptable
alternatives have already helped hundreds of thousands of patients and
new clinical uses expand almost weekly. Consider these few examples:
Have people with juvenile diabetes benefited from adult stem cells?
Yes. Fifteen people with serious Type I (juvenile) diabetes became "insulin
free" after adult pancreatic islet cell transplants; nine still need
no insulin injections (American Diabetes Assoc. Report, June 24, 2001).
How many have benefited with embryonic stem cells? No person has benefited.
Have people with spinal cord injuries benefited from adult stem cells?
Yes.
A young woman rendered paraplegic by a car accident can move her toes
and legs after injection of her own immune-system cells into her severed
spinal cord (Toronto Globe and Mail, June 15, 2001).
How many have benefited with embryonic stem cells? No person has benefited.
Have people with immune deficiency benefited from adult stem cells?
Yes.
Two children born without immune systems ("bubble boy" syndrome) have
left their sterile environments and lead normal lives after bone marrow
stem cell treatment (Science, The Washington Post, April 28, 2000).
How many have benefited with Embryonic stem cells? No person has benefited!
Have people who are visually impaired benefited from adult stem cells?
Yes!
Several legally blind people can now see more clearly after their corneas
were reconstructed with corneal stem cells (New England Journal of Medicine,
July 13, 2000).
How many have benefited with Embryonic stem cells? No person has benefited
Nevertheless, a great push currently exists for embryonic stem cell
research. This push often comes from celebrities with disabilities.
Actors such as the late Christopher Reeve and Michael J. Fox have made
public appearances, even before the American Congress, promoting embryonic
stem cell research. I am sure that in their consciences, they were not
aware that they desired the death of someone else to save their own
lives. Yet, their pleas coupled with their conditions have pulled at
the heart strings of many people who make moral decisions based on feelings,
rather than on rational thinking. This push has even motivated legislators.
Playing on the emotions of others, too, many politicians are willing
to sometimes abandon rational thinking in the pursuit of another vote.
Keep in mind there is no real proof that embryonic stem cell research
will bring about any more benefit than adult stem cell research. Dr.
Ronald McKay, a stem cell researcher at the National Institute of Neurological
Disorders and Stroke, explaining why scientists have allowed society
to believe wrongly that stem cells are likely to treat Alzheimer's disease,
has said, "People need a fairy tale." He added, "Maybe that's not fair,
but they need a storyline that's relatively simple to understand." Michael
Fumento, one of the most skilled debunkers of junk science, contrasts
the use of adult and embryonic stem cells in this way: "Over the horizon
are so-called adult stem cells, extracted from people of any age and
from umbilical cords and placentas. Not only don't they carry the moral
baggage of embryonic stem cells, but research with them is much further
along. Unfortunately, embryonic stem cell researchers have so powerful
a PR machine that many influential people don't even know there is an
alternative."
That said, it is still important to remember that even if embryonic
stem cell research were promising, it would remain immoral, because
it involves the purposeful creation and destruction of an innocent human
being.
To use the words of Huxley, we have entered a "brave new world." While
we have the technology to do something, we do not necessarily have the
moral mandate to do something. Just because we can do it doesn't mean
it ought to be done. Researchers cannot simply think and act as though
they are free to do anything without being subject to moral parameters.
We find ourselves sliding further down the slope of morality - first
came the proliferation of contraception, then abortion, then in-vitro
fertilization (which requires the destruction of many human embryos
in order for someone to conceive) and now embryonic stem cell research.
This is what John Paul II has described as a culture of death.
Yet, we can stand up to this culture and spread a gospel of life that
respects every person, regardless of what they look like or what others
may think of them. By telling others the truth about human life and
the dignity of every human person, no matter how small, no matter how
vulnerable and making choices for ourselves that show we support a culture
of life, we can illumine the darkness of our world. Telling others about
stem cell research is part of this task that Christ gives to us his
followers, the task of spreading the gospel of life.
In regard to our elected officials, we can write to tell them how we
feel about research performed on embryos and make sure that we do not
vote for a person who, while representing us, would promote such research.
It takes a lot of courage to defend life, especially humans who are
not even born. Sometimes, we may experience conflict and misunderstanding
and the words of the Gospel ring true: "You will be hated by all because
of my name, but not a hair of your head will perish. By your endurance,
you will gain your souls."
Let's promote research that enhances the dignity of each person, rather
than destroying the lives of individuals. Let's promote research that
we can all live with.
Fr. Seamus Hogan is associate pastor at Blessed Trinity Roman Catholic
Church in Toronto, where he delivered this homily on Nov. 14. He wishes
to acknowledge the expertise of the United States Conference of Catholic
Bishops "pro-life activities page" at www.usccb.org and Fr. William
Saunder's article, "Stem Cell Research" at www.catholiceducation.org,
without which his homily would not have been possible.